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Small Intestinal Submucosa Decellularized Extracellular Matrix

Small Intestinal Submucosa Decellularized Extracellular Matrix

2024-12-04

 

【Introduction】
The main components of the submucosa of Small Intestinal Submucosa are typeⅠand Ⅲ collagen fibers,a small number of cells,some larger blood vessels,lymph vessels and nerves.Small Intestinal Submucosa Decellularized Extracellular Matrix obtains through a series of industrial processes such as inactivation,degreasing,decellularization to remove residual cells、DNA、α-gal proteins and other immunogenic substances.

 

【Chemical Properties】
Biologically Safe、Fully Degradable and Absorbable

 

【Advantages】
1、Low Immunogenicity:SIS-dECM has gone through virus inactivation, degreasing,decellularization and other processes to remove immunogenic substances,which will not cause immune rejection.
2、Excellent Biocompatibility and Tissue Regeneration:SIS-dECM consists of collagen,glycosaminoglycan,glycoproteins and a variety of growth factors.These components can effectively promote cell adhesion,proliferation and differentiation to provide a microenvironment close to the in vivo environment for cell growth,which can be quickly vascularized to accelerate tissue repair and reconstruction.
3、Degradability: SIS-dECM can be gradually degraded in the body and eventually completely absorbed by the organism.This characteristic makes it particularly suitable for using in tissue engineering requiring long-term repair.
4、High Conformity and Pasticity:The product exhibits good affinity and conformity with tissues, adhering closely to soft tissues in a wet state, thereby enhancing patient comfort.

 

【Grade】

Medical Grade, Sterile

 

【Package and Storage】

Packed as Required, Sealed and Stored at 2~8℃.

 

【Application】
1、Soft Tissue Repair:Oral Repair Film, Hernia Repair Patch (Excellent biological safety and strong wound adhesion can induce regular growth of tissue cells and promote wound healing)
2、Reconstruction of Tissues and Organs:Anastomosis Reinforcement Patch, ECM Hydrogel (It can be degraded and absorbed,to provide a good environment for adhesion, proliferation and differentiation of various cells)
3、Cosmetic Medicine Filler Materials:Injection Anti-wrinkle Biogel (It is high biocompatibility,extremely low risk of infection and rejection, good filling effect,and induce tissue regeneration.)
4、Hemostatic Material:Hemostatic Bandage (Excellent biosafety and unique porous structure effectively promote platelet aggregation and accelerate the coagulation process to achieve hemostasis, and simultaneously promotes wound healing.)

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